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Recent Advances in 3D Printing of Biomaterials


Roger Narayan (Professor - Joint Department of Biomedical Engineering, UNC/NCSU)

Location: 208B

Date: Thursday, February 8

Time: 1:15pm - 2:15pm

Pass Type: Conference (Paid) - Get your pass now!

Conference Track: 3D Printing

Vault Recording: TBD

Additive manufacturing, also known as 3D printing, is an approach that is being considered for fabrication of individualized medical implants and prostheses. The term additive manufacturing is used to describe fabrication of three-dimensional objects via selective joining of solids, liquids, or powders in a layer-by-layer manner. Data obtained from computed tomography or other techniques is currently being used to create patient-specific implants. Microscale and sub-microscale features may be incorporated within these customized implants to promote appropriate cell-prosthesis interactions. Efforts are also underway to utilize additive manufacturing approaches to create "smart" implants. In recent years, techniques such as fused deposition modeling, stereolithography apparatus, selective laser sintering, and laser induced forward transfer, have been used to prepare medical implants and prostheses. For example, two photon polymerization is an additive manufacturing approach that relies on use of ultrashort laser pulses to selectively polymerize photosensitive materials at small length scales. The two photon polymerization process involves both temporal and spatial overlap of photons to initiate chemical reactions between photoinitiator molecules and monomers within a transparent matrix. This approach has recently been to create structures out of biocompatible inorganic-organic hybrid materials (e.g., zirconium oxide hybrid materials) and polymers for medical applications. The use of biocompatible photoinitiators for two photon polymerization will be described. Application-specific studies of two photon polymerization-processed medical devices will be discussed. Our results indicate that additive manufacturing approaches such as two photon polymerization provide unique benefits for processing medical implants and prostheses with small-scale features and unique medical functionalities.